CHST6

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CHST6
Identifiers
Aliases CHST6, MCDC1, carbohydrate sulfotransferase 6
External IDs MGI: 1931825 HomoloGene: 56927 GeneCards: CHST6
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021615

NM_019950

RefSeq (protein)

NP_067628

NP_064334.1
NP_064334

Location (UCSC) Chr 16: 75.47 – 75.5 Mb Chr 8: 111.89 – 111.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Carbohydrate sulfotransferase 6 is an enzyme that in humans is encoded by the CHST6 gene.[3][4][5]

It codes for an enzyme necessary for the production of keratan sulfate. Mutations in the gene lead to macular corneal dystrophy.

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Vance JM, Jonasson F, Lennon F, Sarrica J, Damji KF, Stauffer J, Pericak-Vance MA, Klintworth GK (Jul 1996). "Linkage of a gene for macular corneal dystrophy to chromosome 16". Am J Hum Genet. 58 (4): 757–62. PMC 1914688Freely accessible. PMID 8644739. 
  4. ^ Akama TO, Nishida K, Nakayama J, Watanabe H, Ozaki K, Nakamura T, Dota A, Kawasaki S, Inoue Y, Maeda N, Yamamoto S, Fujiwara T, Thonar EJ, Shimomura Y, Kinoshita S, Tanigami A, Fukuda MN (Nov 2000). "Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene". Nat Genet. 26 (2): 237–41. doi:10.1038/79987. PMID 11017086. 
  5. ^ "Entrez Gene: CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6". 

External links[edit]

Further reading[edit]