CLCN6

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CLCN6
Identifiers
AliasesCLCN6, CLC-6, chloride voltage-gated channel 6
External IDsMGI: 1347049 HomoloGene: 985 GeneCards: CLCN6
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for CLCN6
Genomic location for CLCN6
Band1p36.22Start11,806,096 bp[1]
End11,848,079 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256959
NM_001286
NM_021735
NM_021736
NM_021737

NM_011929

RefSeq (protein)

NP_001243888
NP_001277

NP_036059

Location (UCSC)Chr 1: 11.81 – 11.85 MbChr 4: 148 – 148.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.[5][6]

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000011021 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029016 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Brandt S, Jentsch TJ (Feb 1996). "ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family". FEBS Lett. 377 (1): 15–20. doi:10.1016/0014-5793(95)01298-2. PMID 8543009.
  6. ^ a b "Entrez Gene: CLCN6 chloride channel 6".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.