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Chloride intracellular channel 5
Symbols CLIC5 ; DFNB102; DFNB103; MST130; MSTP130
External IDs OMIM607293 MGI1917912 HomoloGene987 GeneCards: CLIC5 Gene
RNA expression pattern
PBB GE CLIC5 219866 at tn.png
PBB GE CLIC5 217628 at tn.png
More reference expression data
Species Human Mouse
Entrez 53405 224796
Ensembl ENSG00000112782 ENSMUSG00000023959
UniProt Q9NZA1 Q8BXK9
RefSeq (mRNA) NM_001114086 NM_172621
RefSeq (protein) NP_001107558 NP_766209
Location (UCSC) Chr 6:
45.9 – 46.08 Mb
Chr 17:
44.19 – 44.28 Mb
PubMed search [1] [2]

Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene.[1][2]


Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 specifically associates with the cytoskeleton of placenta microvilli.[2] CLIC5 can form ion channel in bilayers and is regulated by actin.

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.