COG4

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COG4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases COG4, CDG2J, COD1, component of oligomeric golgi complex 4
External IDs MGI: 2142808 HomoloGene: 7155 GeneCards: COG4
RNA expression pattern
PBB GE COG4 212189 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001195139
NM_015386

NM_133973
NM_001310607

RefSeq (protein)

NP_001182068
NP_056201

NP_598734.1
NP_001297536
NP_598734

Location (UCSC) Chr 16: 70.48 – 70.52 Mb Chr 8: 110.85 – 110.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.[3][4]

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4 (Ungar et al., 2002).[supplied by OMIM][4]

Interactions[edit]

COG4 has been shown to interact with COG7,[5] COG2,[5] COG1[5] and COG5.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297Freely accessible. PMID 11980916. 
  4. ^ a b "Entrez Gene: COG4 component of oligomeric golgi complex 4". 
  5. ^ a b c d Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. United States. 279 (23): 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. 

Further reading[edit]

External links[edit]