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Coatomer protein complex, subunit gamma 1
Protein COPG PDB 1pzd.png
PDB rendering based on 1pzd.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols COPG1 ; COPG
External IDs OMIM615525 MGI1858696 HomoloGene56745 GeneCards: COPG1 Gene
RNA expression pattern
PBB GE COPG 217749 at tn.png
More reference expression data
Species Human Mouse
Entrez 22820 54161
Ensembl ENSG00000181789 ENSMUSG00000030058
UniProt Q9Y678 Q9QZE5
RefSeq (mRNA) NM_016128 NM_017477
RefSeq (protein) NP_057212 NP_059505
Location (UCSC) Chr 3:
129.25 – 129.28 Mb
Chr 6:
87.89 – 87.91 Mb
PubMed search [1] [2]

Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene.[1][2] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.[1]


COPG has been shown to interact with Dopamine receptor D1,[3] COPZ1[1][4] and COPB1.[1][5]


  1. ^ a b c d Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392. 
  2. ^ "Entrez Gene: COPG coatomer protein complex, subunit gamma". 
  3. ^ Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. (Germany) 81 (2): 77–85. doi:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085. 
  4. ^ Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex". J. Cell Biol. (UNITED STATES) 135 (1): 53–61. doi:10.1083/jcb.135.1.53. ISSN 0021-9525. PMC 2121028. PMID 8858162. 
  5. ^ Lowe, M; Kreis T E (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. (UNITED STATES) 271 (48): 30725–30. doi:10.1074/jbc.271.48.30725. ISSN 0021-9258. PMID 8940050. 

Further reading[edit]