COPS4

COPS4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4D0P, 4D10, 4D18, 4WSN
Identifiers
Aliases	COPS4, CSN4, COP9 signalosome subunit 4, SGN4
External IDs	OMIM: 616008; MGI: 1349414; HomoloGene: 8067; GeneCards: COPS4; OMA:COPS4 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	83,075,818 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	100,695,669 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; vastus lateralis muscle; ; deltoid muscle; ; Skeletal muscle tissue of biceps brachii; ; glutes; ; thoracic diaphragm; ; Skeletal muscle tissue of rectus abdominis; ; tibialis anterior muscle; ; right ventricle; ; secondary oocyte;
	Top expressed in
	spermatid; ; spermatocyte; ; maxillary prominence; ; mandibular prominence; ; tail of embryo; ; otic vesicle; ; seminiferous tubule; ; genital tubercle; ; otic placode; ; supraoptic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; NEDD8-specific protease activity;
Cellular component	cytoplasm; COP9 signalosome; cell junction; synapse; extracellular exosome; cytoplasmic vesicle; synaptic vesicle; nucleus; nucleoplasm; cytosol; nuclear speck;
Biological process	transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; protein deneddylation; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	51138
	26891
	ENSG00000138663
	ENSMUSG00000035297
	Q9BT78
	O88544
	NM_001258006; NM_016129; NM_001330727
	NM_012001; NM_001359203; NM_001359204
	NP_001244935; NP_001317656; NP_057213
	NP_036131; NP_001346132; NP_001346133
	Wikidata
View/Edit Human	View/Edit Mouse

COP9 signalosome complex subunit 4 is a protein that in humans is encoded by the COPS4 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138663 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035297 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wei N, Tsuge T, Serino G, Dohmae N, Takio K, Matsui M, Deng XW (Oct 1998). "The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex". Curr Biol. 8 (16): 919–924. doi:10.1016/S0960-9822(07)00372-7. PMID 9707402.
^ "Entrez Gene: COPS4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)".

References

Further reading