COQ2

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COQ2
Identifiers
Aliases COQ2, CL640, COQ10D1, MSA1, PHB:PPT, coenzyme Q2, polyprenyltransferase
External IDs MGI: 1919133 HomoloGene: 69192 GeneCards: COQ2
RNA expression pattern
PBB GE COQ2 213379 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015697

NM_027978

RefSeq (protein)

NP_056512

NP_082254.2

Location (UCSC) Chr 4: 83.26 – 83.28 Mb Chr 5: 100.65 – 100.68 Mb
PubMed search [1] [2]
Wikidata
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Para-hydroxybenzoate—polyprenyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ2 gene.[3][4]

CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004).[supplied by OMIM][4]

References[edit]

Further reading[edit]