CORO2A

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CORO2A
Identifiers
Aliases CORO2A, CLIPINB, IR10, WDR2, coronin 2A
External IDs MGI: 1345966 HomoloGene: 2546 GeneCards: CORO2A
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003389
NM_052820

NM_001164804
NM_178893

RefSeq (protein)

NP_003380
NP_438171

NP_001158276
NP_849224

Location (UCSC) Chr 9: 98.12 – 98.19 Mb Chr 4: 46.54 – 46.6 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Coronin, actin binding protein, 2A is a protein that in humans is encoded by the CORO2A gene.[3]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].[3]

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