Carboxypeptidase A1

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CPA1
Protein CPA1 PDB 2V77.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCPA1, CPA, carboxypeptidase A1
External IDsMGI: 88478 HomoloGene: 55609 GeneCards: CPA1
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for CPA1
Genomic location for CPA1
Band7q32.2Start130,380,339 bp[1]
End130,388,114 bp[1]
RNA expression pattern
PBB GE CPA1 205615 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001868

NM_025350

RefSeq (protein)

NP_001859

NP_079626

Location (UCSC)Chr 7: 130.38 – 130.39 MbChr 6: 30.64 – 30.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Carboxypeptidase A1 is an enzyme that in humans is encoded by the CPA1 gene.[5]

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase A1 is a monomeric pancreatic exopeptidase. It is involved in zymogen inhibition.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000091704 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054446 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: CPA1 carboxypeptidase A1 (pancreatic)".

Further reading[edit]

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: M14.001