CPNE4

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CPNE4
Identifiers
Aliases CPNE4, COPN4, CPN4, copine 4
External IDs MGI: 1921270 HomoloGene: 26078 GeneCards: CPNE4
Genetically Related Diseases
amyotrophic lateral sclerosis[1]
RNA expression pattern
PBB GE CPNE4 gnf1h09017 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289112
NM_130808
NM_153429

NM_028719

RefSeq (protein)

NP_082995.1
NP_082995

Location (UCSC) Chr 3: 131.53 – 132.29 Mb Chr 9: 104.55 – 105.03 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Copine-4 is a protein that in humans is encoded by the CPNE4 gene.[4][5][6]

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.[6]

References[edit]

  1. ^ "Diseases that are genetically associated with CPNE4 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans". J Biol Chem. 273 (3): 1393–402. doi:10.1074/jbc.273.3.1393. PMID 9430674. 
  5. ^ Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–7. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487. 
  6. ^ a b "Entrez Gene: CPNE4 copine IV". 

Further reading[edit]