CSNK1D

From Wikipedia, the free encyclopedia
Jump to: navigation, search
CSNK1D
Protein CSNK1D PDB 1cki.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CSNK1D, ASPS, CKIdelta, FASPS2, HCKID, casein kinase 1 delta
External IDs OMIM: 600864 MGI: 1355272 HomoloGene: 74841 GeneCards: CSNK1D
EC number 2.7.11.26
Targeted by Drug
PF-4800567[1]
RNA expression pattern
PBB GE CSNK1D 207945 s at fs.png

PBB GE CSNK1D 208774 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001893
NM_139062

NM_027874
NM_139059

RefSeq (protein)

NP_001884
NP_620693

NP_620690.1
NP_082150
NP_620690

Location (UCSC) Chr 17: 82.24 – 82.27 Mb Chr 11: 120.96 – 120.99 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

The CSNK1D gene encodes the casein kinase I isoform delta enzyme in humans.[4]

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene.[5]

Interactions[edit]

CSNK1D has been shown to interact with Gap junction protein, alpha 1.[6]

References[edit]

  1. ^ "Drugs that physically interact with Casein kinase 1 delta view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Fish KJ, Cegielska A, Getman ME, Landes GM, Virshup DM (Jul 1995). "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family". J Biol Chem. 270 (25): 14875–83. doi:10.1074/jbc.270.25.14875. PMID 7797465. 
  5. ^ "Entrez Gene: CSNK1D casein kinase 1, delta". 
  6. ^ Cooper, Cynthia D; Lampe Paul D (Nov 2002). "Casein kinase 1 regulates connexin-43 gap junction assembly". J. Biol. Chem. United States. 277 (47): 44962–8. doi:10.1074/jbc.M209427200. ISSN 0021-9258. PMID 12270943. 

Further reading[edit]