CTP synthase 1

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CTPS1
PDB 2vo1 EBI.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CTPS1, CTPS, IMD24, CTP synthase 1, GATD5
External IDs MGI: 1858304 HomoloGene: 20446 GeneCards: CTPS1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301237
NM_001905

NM_016748

RefSeq (protein)

NP_001288166
NP_001896

NP_058028.2
NP_058028

Location (UCSC) Chr 1: 40.98 – 41.01 Mb Chr 4: 120.54 – 120.57 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

CTP synthase 1 is an enzyme that in human s is encoded by the CTPS gene.[3][4]

Function[edit]

The catalytic conversion of uridine triphosphate (UTP) to cytidine triphosphate (CTP) is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. This enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Yamauchi M, Yamauchi N, Phear G, Spurr NK, Martinsson T, Weith A, Meuth M (December 1991). "Genomic organization and chromosomal localization of the human CTP synthetase gene (CTPS)". Genomics. 11 (4): 1088–96. doi:10.1016/0888-7543(91)90036-E. PMID 1783378. 
  4. ^ a b "Entrez Gene: CTP synthase". 

External links[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.