CUL7

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CUL7
Protein CUL7 PDB 2jng.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CUL7, 3M1, KIAA0076, dJ20C7.5, cullin 7
External IDs MGI: 1913765 HomoloGene: 56683 GeneCards: 9820
RNA expression pattern
PBB GE CUL7 203558 at tn.png

PBB GE CUL7 36084 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001168370
NM_014780

NM_025611

RefSeq (protein)

NP_001161842.1
NP_055595.2

NP_079887.3

Location (UCSC) Chr 6: 43.04 – 43.05 Mb Chr 17: 46.65 – 46.66 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.[1][2][3]

Clinical significance[edit]

It is associated with 3-M syndrome.

Interactions[edit]

CUL7 has been shown to interact with RBX1.[1]

References[edit]

  1. ^ a b Dias DC, Dolios G, Wang R, Pan ZQ (Dec 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proc Natl Acad Sci U S A 99 (26): 16601–6. doi:10.1073/pnas.252646399. PMC 139190. PMID 12481031. 
  2. ^ Arai T, Kasper JS, Skaar JR, Ali SH, Takahashi C, DeCaprio JA (Aug 2003). "Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis". Proc Natl Acad Sci U S A 100 (17): 9855–60. doi:10.1073/pnas.1733908100. PMC 187864. PMID 12904573. 
  3. ^ "Entrez Gene: CUL7 cullin 7". 

Further reading[edit]

External links[edit]