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Cytochrome P450, family 2, subfamily S, polypeptide 1
Symbols CYP2S1 ; CYPIIS1
External IDs OMIM611529 MGI1921384 HomoloGene75274 GeneCards: CYP2S1 Gene
EC number
Species Human Mouse
Entrez 29785 74134
Ensembl ENSG00000167600 ENSMUSG00000040703
UniProt Q96SQ9 Q9DBX6
RefSeq (mRNA) NM_030622 NM_028775
RefSeq (protein) NP_085125 NP_083051
Location (UCSC) Chr 19:
41.19 – 41.21 Mb
Chr 7:
25.8 – 25.82 Mb
PubMed search [1] [2]

Cytochrome P450 2S1 is a protein that in humans is encoded by the CYP2S1 gene.[1][2]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.[2]


  1. ^ Rylander T, Neve EP, Ingelman-Sundberg M, Oscarson M (Feb 2001). "Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1)". Biochem Biophys Res Commun 281 (2): 529–35. doi:10.1006/bbrc.2001.4390. PMID 11181079. 
  2. ^ a b "Entrez Gene: CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1". 

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