Caffeyville is an unincorporated community in Laclede County, Missouri, United States, along the former U.S. Route 66. It is about five miles (8 km) southwest of Lebanon on the south outer road of Interstate 44.
The community has the name of Jessie Floyd Caffey, the proprietor of a gas station.
- U.S. Geological Survey Geographic Names Information System: Caffeyville, Missouri
- Sonderman, Joe (2009). Route 66 in the Missouri Ozarks. Arcadia Publishing. p. 62. ISBN 978-0-7385-6030-4.
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