Calcium(II) chloride, Calcium dichloride, E509
3D model (JSmol)
|E number||E509 (acidity regulators, ...)|
|Molar mass||110.98 g·mol−1|
|Appearance||White powder, hygroscopic|
|Density||2.15 g/cm3 (anhydrous)
2.24 g/cm3 (monohydrate)
1.85 g/cm3 (dihydrate)
1.83 g/cm3 (tetrahydrate)
1.71 g/cm3 (hexahydrate)
|Melting point||772–775 °C (1,422–1,427 °F; 1,045–1,048 K)
260 °C (500 °F; 533 K)
175 °C (347 °F; 448 K)
45.5 °C (113.9 °F; 318.6 K)
30 °C (86 °F; 303 K)
|Boiling point||1,935 °C (3,515 °F; 2,208 K) anhydrous|
74.5 g/100 mL (20 °C)
49.4 g/100 mL (−25 °C)
59.5 g/100 mL (0 °C)
65 g/100 mL (10 °C)
81.1 g/100 mL (25 °C)
102.2 g/100 mL (30.2 °C)
90.8 g/100 mL (20 °C)
114.4 g/100 mL (40 °C)
134.5 g/100 mL (60 °C)
152.4 g/100 mL (100 °C)
|Solubility||Soluble in CH3COOH, alcohols
Insoluble in liquid NH3, DMSO, CH3COOC2H5
|Solubility in ethanol||18.3 g/100 g (0 °C)
25.8 g/100 g (20 °C)
35.3 g/100 g (40 °C)
56.2 g/100 g (70 °C)
|Solubility in methanol||21.8 g/100 g (0 °C)
29.2 g/100 g (20 °C)
38.5 g/100 g (40 °C)
|Solubility in acetone||0.1 g/kg (20 °C)|
|Solubility in pyridine||16.6 g/kg|
|Acidity (pKa)||8–9 (anhydrous)
Refractive index (nD)
|Viscosity||3.34 cP (787 °C)
1.44 cP (967 °C)
|Orthorhombic (rutile, anhydrous), oP6
Tetragonal (anhydrous, > 217 °C), oP6
|Pnnm, No. 58 (anhydrous)
P42/mnm, No. 136 (anhydrous, > 217 °C)
|2/m 2/m 2/m (anhydrous)
4/m 2/m 2/m (anhydrous, > 217 °C)
a = 6.259 Å, b = 6.444 Å, c = 4.17 Å (anhydrous, 17 °C)
α = 90°, β = 90°, γ = 90°
|Octahedral (Ca2+, anhydrous)|
|72.89 J/mol·K (anhydrous)
106.23 J/mol·K (monohydrate)
172.92 J/mol·K (dihydrate)
251.17 J/mol·K (tetrahydrate)
300.7 J/mol·K (hexahydrate)
Std enthalpy of
|−795.42 kJ/mol (anhydrous)
−1110.98 kJ/mol (monohydrate)
−1403.98 kJ/mol (dihydrate)
−2009.99 kJ/mol (tetrahydrate)
− 2608.01 kJ/mol (hexahydrate)
Gibbs free energy (ΔfG˚)
|A12AA07 (WHO) B05XA07 (WHO), G04BA03 (WHO)|
|Safety data sheet||See: data page|
|GHS signal word||Warning|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|1000 mg/kg (rats, oral)|
|Supplementary data page|
|Refractive index (n),
Dielectric constant (εr), etc.
|UV, IR, NMR, MS|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Calcium chloride is commonly encountered as a hydrated solid with generic formula CaCl2(H2O)x, where x = 0, 1, 2, 4, and 6. These compounds are mainly used for de-icing and dust control. Because the anhydrous salt is hygroscopic, it is used as a desiccant.
- 1 Uses
- 2 Hazards
- 3 Properties
- 4 Preparation
- 5 See also
- 6 References
- 7 External links
De-icing and freezing point depression
By depressing the freezing point of water, calcium chloride is used to prevent ice formation and is used to de-ice. This application consumes the greatest amount of calcium chloride. Calcium chloride is relatively harmless to plants and soil. As a de-icing agent, it is more effective at lower temperatures than sodium chloride. When distributed for this use, it usually takes the form of small, white spheres a few millimeters in diameter, called prills. Solutions of calcium chloride can prevent freezing at temperature as low as −52 °C (−62 °F), making it ideal for filling agricultural implement tires as a liquid ballast, aiding traction in cold climates.
The second largest application of calcium chloride exploits hygroscopic properties and the tackiness of its hydrates. A concentrated solution keeps a liquid layer on the surface of dirt roads, which suppresses formation of dust. It keeps the finer dust particles on the road, providing a cushioning layer. If these are allowed to blow away, the large aggregate begins to shift around and the road breaks down. Using calcium chloride reduces the need for grading by as much as 50% and the need for fill-in materials as much as 80%
Calcium chloride is used to increase the water hardness in swimming pools. This process reduces the erosion of the concrete in the pool. By Le Chatelier's principle and the common ion effect, increasing the concentration of calcium in the water will reduce the dissolution of calcium compounds essential to the structure of concrete.
The average intake of calcium chloride as food additives has been estimated to be 160–345 mg/day. Calcium chloride is permitted as a food additive in the European Union for use as a sequestrant and firming agent with the E number E509. It is considered as generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. Its use in organic crop production is generally prohibited under the US National Organic Program.
In marine aquariums, calcium chloride is one way to introduce bioavailable calcium for calcium carbonate-shelled animals such as mollusks and some cnidarians. Calcium hydroxide (kalkwasser mix) or a calcium reactor can also be used.
As a firming agent, calcium chloride is used in canned vegetables, in firming soybean curds into tofu and in producing a caviar substitute from vegetable or fruit juices. It is commonly used as an electrolyte in sports drinks and other beverages, including bottled water. The extremely salty taste of calcium chloride is used to flavor pickles without increasing the food's sodium content. Calcium chloride's freezing-point depression properties are used to slow the freezing of the caramel in caramel-filled chocolate bars. Also, it is frequently added to sliced apples to maintain texture.
In brewing beer, calcium chloride is sometimes used to correct mineral deficiencies in the brewing water. It affects flavor and chemical reactions during the brewing process, and can also affect yeast function during fermentation.
In cheesemaking, calcium chloride is sometimes added to processed (pasteurized/homogenized) milk to restore the natural balance between calcium and protein in casein. It is added before the coagulant.
Drying tubes are frequently packed with calcium chloride. Kelp is dried with calcium chloride for use in producing sodium carbonate. Anhydrous calcium chloride has been approved by the FDA as a packaging aid to ensure dryness (CPG 7117.02).
It is injected to treat internal hydrofluoric acid burns. It can be used to treat magnesium intoxication. Calcium chloride injection may improve the appearance of an electrocardiogram. It can help to protect the myocardium from dangerously high levels of serum potassium in hyperkalemia. Calcium chloride can be used to quickly treat calcium channel blocker toxicity, from the side effects of drugs such as diltiazem.
While intravenous calcium has been used in cardiac arrest its general use is not recommended. Cases of cardiac arrest in which it is still recommended include high blood potassium, low blood calcium such as may occur following blood transfusions, and calcium channel blocker overdose. There is the potential that general use could worsen outcomes. If calcium is used calcium chloride is generally the recommended form.
Aqueous calcium chloride is used in genetic transformation of cells by increasing the cell membrane permeability, inducing competence for DNA uptake (allowing DNA fragments to enter the cell more readily).
Calcium chloride is used in concrete mixes to accelerate the initial setting, but chloride ions lead to corrosion of steel rebar, so it should not be used in reinforced concrete. The anhydrous form of calcium chloride may also be used for this purpose and can provide a measure of the moisture in concrete.
Calcium chloride is included as an additive in plastics and in fire extinguishers, in wastewater treatment as a drainage aid, in blast furnaces as an additive to control scaffolding (clumping and adhesion of materials that prevent the furnace charge from descending), and in fabric softener as a thinner.
In the oil industry, calcium chloride is used to increase the density of solids-free brines. It is also used to provide inhibition of swelling clays in the water phase of invert emulsion drilling fluids.
CaCl2 acts as flux material (decreasing melting point) in the Davy process for the industrial production of sodium metal, through the electrolysis of molten NaCl.
Calcium chloride is also used in the production of activated charcoal.
Calcium chloride is also an ingredient used in ceramic slipware. It suspends clay particles so that they float within the solution making it easier to use in a variety of slipcasting techniques.
Calcium chloride dihydrate (20% by weight) dissolved in ethanol (95% ABV) has been used as a sterilant for male animals. The solution is injected into the testes of the animal. Within 1 month, necrosis of testicular tissue results in sterilization.
Calcium chloride can act as an irritant by desiccating moist skin. Solid calcium chloride dissolves exothermically, and burns can result in the mouth and esophagus if it is ingested. Ingestion of concentrated solutions or solid products may cause gastrointestinal irritation or ulceration.
Calcium chloride dissolves in water, producing chloride and the aquo complex [Ca(H2O)6]2+. In this way, these solutions are sources of "free" calcium and free chloride ions. This description is illustrated by the fact that these solutions react with phosphate sources to give a solid precipitate of calcium phosphate:
- 3 CaCl2 + 2 PO3−
4 → Ca3(PO4)2 + 6 Cl−
Calcium chloride has a very high enthalpy change of solution, indicated by considerable temperature rise accompanying dissolution of the anhydrous salt in water. This property is the basis for its largest scale application.
- CaCl2 → Ca + Cl2
- 2 NaCl + CaCO3 → Na2CO3 + CaCl2
In the US, most of calcium chloride is obtained by purification from brine. A Dow Chemical Company manufacturing facility in Michigan houses about 35% of the total U.S. production capacity for calcium chloride.
As with most bulk commodity salt products, trace amounts of other cations from the alkali metals and alkaline earth metals (groups 1 and 2) and other anions from the halogens (group 17) typically occur, but the concentrations are trifling.
Calcium chloride occurs as the rare evaporite minerals sinjarite (dihydrate) and antarcticite (hexahydrate). The related minerals chlorocalcite (potassium calcium chloride, KCaCl3) and tachyhydrite (calcium magnesium chloride, CaMg2Cl6·12H2O) are also very rare.
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- Anatolievich, Kiper Ruslan. "Properties of substance: calcium chloride". chemister.ru. Retrieved 2014-07-07.
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- "humantouchofchemistry.com Keeping Things Dry". Retrieved 2014-10-23.
- "Dust: Don't Eat It! Control It!". Road Management & Engineering Journal. US Roads (TranSafety Inc.). 1 June 1998. Retrieved 9 August 2006.
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- 21 CFR § 184.1193
- 7 CFR § 205.602
- "Apple Caviar Technique". StarChefs Studio. StarChefs.com. April 2004. Retrieved 9 August 2006.
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- "Accelerating Concrete Set Time". Federal Highway Administration. 1 June 1999. Retrieved 16 January 2007.
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- Koger, Nov 1977, "Calcium Chloride, Practical Necrotizing Agent", Journal of the American Association of Bovine Practitioners (USA), (Nov 1977), v. 12, p. 118–119
- Jana, K.; Samanta, P.K. (2011). "Clinical evaluation of non-surgical sterilization of male cats with single intra-testicular injection of calcium chloride". BMC Vet Res. 7: 39. PMC . PMID 21774835. doi:10.1186/1746-6148-7-39.
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- Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 0-08-037941-9.
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