Calfactant

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Calfactant
Clinical data
Trade names Infasurf
Pregnancy
category
  • N
ATC code
  • none
Legal status
Legal status
Identifiers
ChemSpider
  • none
UNII
ChEMBL
 NYesY (what is this?)  (verify)

Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]

Mechanism of action[edit]

Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.[2]

References[edit]

  1. ^ http://www.infasurf.com/home
  2. ^ a b Drugs.com: Calfactant
  3. ^ Schurch, S.; Lee, M.; Gehr, P. (1992). "Pulmonary surfactant: Surface properties and function of alveolar and airway surfactant". Pure and Applied Chemistry. 64 (11): 1745. doi:10.1351/pac199264111745.