The song was written by Davide Petrella, Dardust, Fabri Fibra, Mahmood, Sfera Ebbasta and Charlie Charles.[3]
Its release was preceded by a series of teasers through Charlie Charles' social network accounts. Its title and featured artists were announced on 23 April 2019, three days before its release.[4]
Charlie Charles described "Calipso" as "a metaphor to tell how easy it is to let yourself be tempted by the wrong roads when you are a kid which starts from the suburbs, and how easy it is to negatively judge who comes from nothing".[5]