Call-Exner bodies

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Call–Exner bodies marked with black circles in an intermediate-high magnification micrograph of a granulosa cell tumour, a type of sex cord stromal tumour. H&E stain.

Call–Exner bodies are small eosinophilic fluid-filled spaces between granulosa cells.[1] The granulosa cells are usually arranged haphazardly around the space.

They are pathognomonic for Granulosa cell tumors.

They are composed of membrane-packaged secretion of granulosa cells and have relations to the formation of liquor folliculi which are seen among closely arranged granulosa cells.

They are named for Emma Louise Call (1847-1937), an American Physician, and Sigmund Exner.[2][3]


  1. ^ > Call–Exner body Citing: The American Heritage Medical Dictionary. Copyright 2007
  2. ^ Archived version of the Call-Exner bodies page on Who Named It?
  3. ^ Emma Louise Call and Sigmund Exner: Zur Kenntniss des Graafschen Follikels und des Corpus luteum beim Kaninchen. Sitzungsberichte der kaiserlichen Akademie der Wissenschaften. Mathematish naturwssenschaftliche Classe, Wien, 1875, 72: 321-328.

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