Accola had guest appearances in a number of television series such as How I Met Your Mother, Supernatural and Drop Dead Diva. In July 2009 she starred in the independent horror film Deadgirl which centers on two high school boys who discover an immortal woman in an abandoned asylum. That same year again King had a bit-role in The Hannah Montana Movie. In 2009 she was cast in The CW television series The Vampire Diaries as Caroline Forbes, a teenage vampire. The series was an immediate success with the series premiere reaching 4.91 million viewers. Critical reception for the show was mixed, but as the show commenced, critics were positive. For Accola's performance, reception from critics and fans alike was very positive and has remained that way, receiving many awards for her performance. In June 2012 she joined the YouTube series Dating Rules From My Future Self as Chloe Cunningham a 26-year-old girl who believes love does not exist. The series centers on a girl receiving romance advice from herself ten years in the future via text message. The first season of the series went on to receive over 14 million views.[clarification needed]
Candice began dating musician Joe King of The Fray after they met at a Super Bowl event in February 2011. They became engaged in May 2013, and married on October 18, 2014 in New Orleans, Louisiana. Upon her marriage, she became a stepmother to Joe King's two daughters from his first marriage. In August 2015, it was announced that Candice and Joe were expecting their first child together. On January 15, 2016, Accola gave birth to a daughter.
Though her parents are Republicans, Candice herself has shown support for President Barack Obama, and supports gay rights.