Candicidin

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Candicidin
Candicidin.png
Systematic (IUPAC) name
33-[(3-Amino-3,6-dideoxy-D-mannopyranosyl)oxy]-17-[6-(4-aminophenyl)-4-hydroxy-1,3-dimethyl-6-oxohexyl]-1,3,5,7,37-pentahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Identifiers
CAS Number 1403-17-4 YesY
ATC code G01AA04
PubChem CID 441142
DrugBank DB01152 YesY
ChemSpider 10128184 YesY
UNII 48N2IYJ202 YesY
ChEMBL CHEMBL1200647 N
Chemical data
Formula C59H84N2O18
Molar mass 1109.32 g/mol
 NYesY (what is this?)  (verify)

Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.[1]

This bioactive compound was named candicidin, because of its high activity on Candida albicans.[2]

References[edit]

  1. ^ "Product information Candicidin" (pdf). Toku-E. 2012-01-11. Retrieved 2012-06-11. 
  2. ^ Selman A. Waksman, Hubert A. Lechevalier & Carl P. Schaffner: Candicidin and other Polyenic Antifungal Antibiotics, 1965, 33, 219-226