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Fungemia ( Fungaemia in the UK and other Commonwealth countries) is the presence of fungi or yeasts in the blood. The most common type, also known as Candidemia, Candedemia, or Invasive Candidiasis, is caused by species, but infections by other fungi, including Candida , Saccharomyces and Aspergillus , are also called fungemia. It is most commonly seen in Cryptococcus immunosuppressed or immunocompromised patients with severe neutropenia, oncology patients, or in patients with intravenous catheters. It has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia.
Diagnosis is difficult, as routine blood cultures have poor sensitivity.
Treatment [ edit ]
Treatment involves use of
antifungals such as fluconazole and amphotericin.
Risk factors [ edit ]
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The three most important risk factors are:
Other risk factors are:
Pathogens [ edit ]
The most commonly known
pathogen is , causing roughly 70% of fungemias, followed by Candida albicans with 10%, Candida glabrata with 1% and Aspergillus as the fourth most common. However, the frequency of infection by Saccharomyces C. glabrata, , Saccharomyces boulardii , Candida tropicalis and C. krusei is increasing, perhaps because significant use of C. parapsilosis fluconazole is common or due to increase in antibiotic use.
Symptoms [ edit ]
Symptoms can range from mild to extreme—often described as extreme
flu-like symptoms. Many symptoms may be associated with fungemia, including pain, mental disorders, chronic fatigue, and infections. Skin infections can include persistent or non-healing wounds and lesions, sweating, itching, and unusual discharge or drainage.
See also [ edit ]
External links [ edit ]