Potassium canrenoate

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Potassium canrenoate
Canrenoate potassium.png
Systematic (IUPAC) name
potassium 3-[(8R,9S,10R,13S,14S,17R)-
17-hydroxy-10,13-dimethyl-3-oxo-2,8,9,
11,12,14,15,16-octahydro-1H-cyclopenta[a]
phenanthren-17-yl]propanoate
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Intravenous
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal and fecal
Identifiers
CAS Registry Number 2181-04-6 N
ATC code C03DA02
PubChem CID: 656614
DrugBank DB09015 N
ChemSpider 570975 YesY
UNII M671F9NLEA N
ChEMBL CHEMBL1371200 N
Synonyms SC-14266
Chemical data
Formula C22H29KO4
Molecular mass 396.5616 g/mol
 N (what is this?)  (verify)

Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), the potassium salt of canrenoic acid, is an aldosterone antagonist.[1] Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Potassium canrenoate is not licensed in the UK, but may sometimes be prescribed off-licence to treat oedema. It is given intravenously.

See also[edit]

References[edit]

  1. ^ R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. pp. 656–. ISBN 978-0-412-27060-4.