From Wikipedia, the free encyclopedia
Jump to: navigation, search
Skeletal formula of canrenone
Ball-and-stick model of the canrenone molecule
Systematic (IUPAC) name
Pharmacokinetic data
Protein binding 95%
Biological half-life 10-35 hours
CAS Registry Number 976-71-6 N
ATC code C03DA03
PubChem CID: 13789
ChemSpider 13192 YesY
UNII 78O20X9J0U YesY
Synonyms RP-11614, SC-9376
Chemical data
Formula C22H28O3
Molecular mass 340.456 g/mol
 N (what is this?)  (verify)

Canrenone (INN, USAN) (brand names Contaren, Luvion, Phanurane, Spiroletan) is an aldosterone antagonist with additional antiandrogen properties which is used as a diuretic in Europe.[1][2]

Carenone is a major active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is believed to be partially responsible for their effects.

See also[edit]


  1. ^ R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. pp. 656–. ISBN 978-0-412-27060-4. 
  2. ^ Romanelli RG, Gentilini P (May 2004). "Cross reactivity due to positive canrenone interference". Gut 53 (5): 772–3. PMC 1774040. PMID 15082604.