Cape Fear may refer to:
- Cape Fear (headland), a promontory of the coast of North Carolina in the United States, the original source of the name
- Cape Fear (region), region of North Carolina surrounding Wilmington, North Carolina, adjacent to the actual cape
- Cape Fear River, a river that empties into the Atlantic Ocean near the cape
- Northeast Cape Fear River, a river that splits from the Cape Fear River
- Cape Fear Indians, an Indian tribe that lived along the Cape Fear River
Art, entertainment, and media
- Cape Fear (1962 film), a film directed by J. Lee Thompson, starring Gregory Peck and Robert Mitchum
- Cape Fear (1991 film), a remake of the original, directed by Martin Scorsese, starring Robert De Niro and Nick Nolte
- Cape Fear (album), a 2007 album by Canadian indie rock group Germans
- "Cape Feare", a 1993 episode of The Simpsons, based on the films
- Cape Fear Crocs, a former minor league baseball team
- South Georgia Wildcats, an indoor football team in Arena Football 2 previously known as the Cape Fear Wildcats
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