Capravirine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Capravirine
Capravirine.png
Names
IUPAC name
[5-(3,5-Dichlorophenyl)sulfanyl-4-propan-2-yl-1-(pyridin-4-ylmethyl)imidazol-2-yl]methyl carbamate
Identifiers
178979-85-6 YesY
3D model (Jmol) Interactive image
ChEMBL ChEMBL435128 N
ChemSpider 1717 N
PubChem 1783
UNII VHC779598X N
Properties
C20H20Cl2N4O2S
Molar mass 451.37 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Capravirine was a non-nucleoside reverse transcriptase inhibitor which reached phase II trials before development was discontinued by Pfizer. Both phase IIb trials which were conducted failed to demonstrate that therapy with capravirine provided any significant advantage over existing triple-drug HIV therapies, and pharmacology studies showed that capravirine may interact with other HIV drugs.[medical citation needed]