Caramiphen

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Caramiphen
Clinical data
Trade namesCarafen
ATC code
  • None
Identifiers
  • 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.922 Edit this at Wikidata
Chemical and physical data
FormulaC18H27NO2
Molar mass289.413 g/mol g·mol−1
3D model (JSmol)
  • O=C(OCCN(CC)CC)C2(c1ccccc1)CCCC2
  • InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3
  • Key:OFAIGZWCDGNZGT-UHFFFAOYSA-N

Caramiphen is an anticholinergic drug used in the treatment of Parkinson's disease.[1] In combination with phenylpropanolamine it is used as a cough suppressant and nasal decongestant to treat symptoms associated with respiratory illnesses such as cold, allergies, hay fever, and sinusitis.[2]

Synthesis

H. Martin and F. Hafliger, U.S. patent 2,404,588 (1946).

See also

References

  1. ^ "Caramiphen". drugs.com. Retrieved 26 September 2012.
  2. ^ "Caramiphen with phenylpropanolamine-oral, Ordrine AT, Rescaps-D, Tuss Vernade, Tusso-Gest". medicine.net. Retrieved 26 September 2012.
  3. ^ V. Petrow, 0. Stephenson, and A. M. Wild, U.S. patent 2,885,404 (1959).