Carbocisteine

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Carbocisteine
Carboxymethylcystein Formulae.png
Names
IUPAC name
(R)-2-Amino-3-(carboxymethylsulfanyl)propanoic acid
Other names
S-Carboxymethyl-L-cysteine; Mucodyne, Solmux, Rhinathiol, Humex, Lisomucil, Fluditec, Exputex, Mucolit, Reodyn, Carbotoux, Flemex, Carbolin, Muflex
Identifiers
ATC code R05CB03
CAS number 638-23-3 (R) YesY
2387-59-9 (RS)
ChEBI CHEBI:16163 YesY
ChEMBL ChEMBL396416 YesY
ChemSpider 168055 YesY
DrugBank DB04339 YesY
Jmol-3D images Image
Image
KEGG D06393 YesY
PubChem 193653
Properties
C5H9NO4S
Molar mass 179.19 g·mol−1
Appearance Colorless solid
Melting point 204 to 207 °C (399 to 405 °F; 477 to 480 K)
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references
Carbocisteine molecule, in 3D

Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.

Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.[1]

Trade names[edit]

Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam[2]

Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.

Mucoral: Portugal

Mucosol: Egypt

Solmux, Loviscol: Philippines

Humotusin: Romania

References[edit]

  1. ^ Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2
  2. ^ http://www.drugs.com/international/rhinathiol.html