Carbonic anhydrase VI

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carbonic anhydrase VI
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CA6, CA-VI, GUSTIN, carbonic anhydrase 6
External IDs MGI: 1333786 HomoloGene: 20324 GeneCards: 765
RNA expression pattern
PBB GE CA6 206873 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001215
NM_001270500
NM_001270501
NM_001270502

NM_009802

RefSeq (protein)

NP_001206.2
NP_001257429.1
NP_001257430.1

NP_033932.2

Location (UCSC) Chr 1: 8.95 – 8.98 Mb Chr 4: 150.19 – 150.2 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Carbonic anhydrase 6 (also called 'Gustin') is an enzyme that in humans is encoded by the CA6 gene.[1][2]

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is abundantly found in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide, though its function in saliva is unknown.[2] It has been suggested that CA VI participates in the maintenance of appropriate pH homeostasis on tooth surfaces as well as in the mucosa of the gastrointestinal canal.

References[edit]

  1. ^ White PS, Jensen SJ, Rajalingam V, Stairs D, Sulman EP, Maris JM, Biegel JA, Wooster R, Brodeur GM (Oct 1998). "Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2". Cytogenet Cell Genet 81 (1): 60–4. doi:10.1159/000014989. PMID 9691177. 
  2. ^ a b "Entrez Gene: CA6 carbonic anhydrase VI". 

Further reading[edit]