Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone

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Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone[1]
Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone.svg
Names
IUPAC name
2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile
Identifiers
370-86-5 YesY
ChEBI CHEBI:75458 N
ChEMBL ChEMBL457504 YesY
ChemSpider 3213 YesY
Jmol 3D model Interactive image
Interactive image
MeSH FCCP
PubChem 3330
Properties
C10H5F3N4O
Molar mass 254.16811 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation.[2] It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.[3]

See also[edit]

References[edit]

  1. ^ FCCP - Compound Summary, PubChem.
  2. ^ MeSH Descriptor Data, MeSH.
  3. ^ Heytler, P G (1962). "A new class of uncoupling agents — Carbonyl cyanide phenylhydrazones". Biochemical and Biophysical Research Communications 7 (4): 272–275. doi:10.1016/0006-291X(62)90189-4.