Carboxypeptidase A2

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CPA2
Protein CPA2 PDB 1aye.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CPA2
External IDs MGI: 3617840 HomoloGene: 37541 GeneCards: 1358
RNA expression pattern
PBB GE CPA2 206212 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001869

NM_001024698

RefSeq (protein)

NP_001860.2

NP_001019869.1

Location (UCSC) Chr 7: 130.27 – 130.29 Mb Chr 6: 30.54 – 30.56 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Carboxypeptidase A2 is an enzyme that in humans is encoded by the CPA2 gene.[3][4][5]

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Catasus L, Vendrell J, Aviles FX, Carreira S, Puigserver A, Billeter M (Apr 1995). "The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model". J Biol Chem. 270 (12): 6651–7. doi:10.1074/jbc.270.12.6651. PMID 7896805. 
  4. ^ Hayashida S, Yamasaki K, Asada Y, Soeda E, Niikawa N, Kishino T (Aug 2000). "Construction of a physical and transcript map flanking the imprinted MEST/PEG1 region at 7q32". Genomics. 66 (2): 221–5. doi:10.1006/geno.2000.6206. PMID 10860668. 
  5. ^ a b "Entrez Gene: CPA2 carboxypeptidase A2 (pancreatic)". 

Further reading[edit]

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: M14.002