Adipostatin A

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Adipostatin A
Chemical structure of adipostatin A
Names
Preferred IUPAC name
5-Pentadecylbenzene-1,3-diol
Other names
Cardol
5-n-Pentadecylresorcinol
5-Pentadecylresorcinol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.019.636
Properties
C21H36O2
Molar mass 320.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Adipostatin A is an alkylresorcinol, a type of phenolic lipids composed of long aliphatic chains and phenolic rings. Chemically, it is similar in structure to urushiol, the irritant found in poison ivy.

Adipostatin A can be found in Gingko biloba fruits as well as in Streptomyces cyaneus.[1] It is also found in cashew nutshell liquid (Anacardium occidentale), in Anacardium othonianum and in Ardisia elliptica.[2]

It is an inhibitor of glycerol-3-phosphate dehydrogenase.[3]

References[edit]

  1. ^ Tanaka, A; Arai, Y; Kim, SN; Ham, J; Usuki, T (2011). "Synthesis and biological evaluation of bilobol and adipostatin A". Journal of Asian natural products research. 13 (4): 290–6. PMID 21462031. doi:10.1080/10286020.2011.554828. 
  2. ^ Koh Hwee Ling, Chua Tung Kian, and Tan Chay Hoon. "A Guide to Medicinal Plants: An Illustrated, Scientific and Medicinal Approach", p. 14. World Scientific Publishing 2009, ISBN 981-283-709-4. Preview available at Google Books
  3. ^ Tsuge, N; Mizokami, M; Imai, S; Shimazu, A; Seto, H (1992). "Adipostatins a and B, new inhibitors of glycerol-3-phosphate dehydrogenase". The Journal of antibiotics. 45 (6): 886–91. PMID 1500355. doi:10.7164/antibiotics.45.886.