Caricain

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Caricain
Identifiers
EC number 3.4.22.30
CAS number 39307-22-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Caricain (EC 3.4.22.30, papaya peptidase A, papaya peptidase II, papaya proteinase, papaya proteinase III, papaya proteinase 3, proteinase omega, papaya proteinase A, chymopapain S, Pp) is an enzyme.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain

This enzyme is isolated from papaya plant, Carica papaya.

References[edit]

  1. ^ Schack, P. (1967). "Fractionation of proteolytic enzymes of dried papaya latex. Isolation and preliminary characterization of a new proteolytic enzyme". C. R. Trav. Carlesberg. 36: 67–83. PMID 6043136. 
  2. ^ Robinson, G.W. (1975). "Isolation and characterization of papaya peptidase A from commercial chymopapain". Biochemistry. 14: 3695–3700. PMID 240390. doi:10.1021/bi00687a028. 
  3. ^ Polgár, L. (1984). "Problems of classification of papaya latex proteinases". Biochem. J. 221: 555–556. PMC 1144075Freely accessible. PMID 6383350. 
  4. ^ Brocklehurst, K.; Salih, E.; McKee, R.; Smith, H. (1985). "Fresh non-fruit latex of Carica papaya contains papain, multiple forms of chymopapain A and papaya proteinase". Biochem. J. 228: 525–527. PMC 1145013Freely accessible. PMID 4015629. 
  5. ^ Zucker, S.; Buttle, D.J.; Nicklin, M.J.H.; Barrett, A.J. (1985). "Proteolytic activities of papain, chymopapain and papaya proteinase III". Biochim. Biophys. Acta. 828: 196–204. PMID 3919769. doi:10.1016/0167-4838(85)90057-3. 
  6. ^ Dubois, T.; Kleinschmidt, T.; Schnek, A.G.; Looze, Y.; Braunitzer, G. (1988). "The thiol proteinases from the latex of Carica papaya L. II. The primary structure of proteinase". Biol. Chem. Hoppe-Seyler. 369: 741–754. PMID 3063283. doi:10.1515/bchm3.1988.369.2.741. 

External links[edit]