Carl Andersen was the son of carpenter Andreas Ferdinand Andersen and Ane Marie Hansen. He became a mason apprentice in 1896 and graduated from Odense Tekniske Skole in 1900. He was employed as construction overseer by master builder Thaaning in Kerteminde in 1900-01 and as a draftsman for architect Emanuel Momberg in Odense in 1901-02. In 1904-06 he was employed by several different architects in Copenhagen including Anders Berthelsen and in 1906-09 as drawer and overseer by H.C. Glahn, Nykøbing Falster in 1906–1909. From 1909 until his death Carl Andersen operated his own architects business in Nykøbing Falster; from 1940 with his son Jørgen Friis Andersen. The business later became Arkitektfirmaet Friis Andersen A/S which still operated in the 2010s. Carl Andersen worked extensively on Lolland in the early 1900s and had many different assignments. Stylistically he worked mainly with neo-baroque but later adopted elements from Functionalism.