Carl Nägeli

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Carl Wilhelm von Nägeli
Born26 or (1817-03-27)27 March 1817
Died10 May 1891(1891-05-10) (aged 74)
Known forresearch on plant anatomy
Scientific career

Carl Wilhelm von Nägeli[1][2][3] (26 or 27 March 1817 – 10 May 1891)[3][4][5] was a Swiss botanist. He studied cell division and pollination but became known as the man who discouraged Gregor Mendel from further work on genetics. He rejected natural selection as a mechanism of evolution, favouring orthogenesis driven by a supposed "inner perfecting principle".

Birth and education[edit]

Nägeli was born in Kilchberg near Zürich, where he studied medicine at the University of Zürich. From 1839, he studied botany under A. P. de Candolle at Geneva, and graduated with a botanical thesis at Zürich in 1840. His attention having been directed by Matthias Jakob Schleiden, then professor of botany at Jena, to the microscopical study of plants, he engaged more particularly in that branch of research. He also coined the term "meristematic tissue" in 1858.

Academic career[edit]

Soon after graduation he became Privatdozent and subsequently professor extraordinary, in the University of Zürich; later he was called to fill the chair of botany at the University of Freiburg; and in 1857 he was promoted to Munich, where he remained as professor until his death.


It was thought that Nägeli had first observed cell division during the formation of pollen, in 1842.[6] However, this is disputed by Henry Harris, who writes: "What Nägeli saw and did not see in plant material at about the same time [as Robert Remak] is somewhat obscure... I conclude... that, unlike Remak, he did not observe nuclear division... it is clear that Nägeli did not in 1844 have any idea of the importance of the nucleus in the life of the cell."[7]

In 1857, Nägeli first described microsporidia, the causative agent of pebrine disease in silkworms, which has historically devastated the silk industry in Europe.[8]

Among his other contributions to science were a series of papers in the Zeitschrift für wissenschaftliche Botanik[9] (1844–1846); Die neueren Algensysteme (1847); Gattungen einzelliger Algen (1849); Pflanzenphysiologische Untersuchungen (1855–1858), with Carl Eduard Cramer; Beiträge zur wissenschaftlichen Botanik[10] (1858–1868); a number of papers contributed to the Royal Bavarian Academy of Sciences, forming three volumes of Botanische Mitteilungen (1861–1881); and, finally, his volume, Mechanisch-physiologische Theorie der Abstammungslehre,[11] published in 1884. However, perhaps Nägeli is best known nowadays for his unproductive correspondence (1866–1873) with Gregor Mendel concerning the latter's celebrated work on Pisum sativum, the garden pea.

The writer Simon Mawer, in his book Gregor Mendel: planting the seeds of genetics (2006), gives us an interesting and detailed account of Nägeli's correspondence with Mendel. Mawer underlines that, at the time Nägeli was writing to the friar from Moravia, Nägeli "must have been preparing his great work entitled A mechanico-physiological theory of organic evolution (published in 1884, the year of Mendel's death) in which he proposes the concept of the 'idioplasm' as the hypothetical transmitter of inherited characters". Mawer notes that, in this Nägeli book, there is not a single mention of the work of Gregor Mendel. That prompted him to write: "We can forgive von Nägeli for being obtuse and supercilious. We can forgive him for being ignorant, a scientist of his time who did not really have the equipment to understand the significance of what Mendel had done despite the fact that he (von Nägeli) speculated extensively about inheritance. But omitting an account of Mendel's work from his book is, perhaps, unforgivable." (Mawer 2006, p. 81)

Nägeli and Hugo von Mohl were the first scientists to distinguish the plant cell wall from the inner contents, which was named the protoplasm in 1846. Nägeli believed that cells receive their hereditary characters from a part of the protoplasm which he called the idioplasma.[12] Nägeli was an advocate of orthogenesis and an opponent of Darwinism. He developed an "inner perfecting principle" which he believed directed evolution. He wrote that many evolutionary developments were nonadaptive and variation was internally programmed.[13]

Nägeli also coined the terms 'Meristem', 'Xylem' and 'Phloem' (all in 1858) while he and Hofmeister gave the 'Apical Cell Theory' (1846) which aimed to explain origin and functioning of the shoot apex meristem in plants.

See also[edit]


  1. ^ Naegeli, Carl Wilhelm von (20 September 1884). Mechanisch-physiologische Theorie der Abstammungslehre – via Max Planck Institute for the History of Science: Virtual Laboratory Library.
  2. ^ "IPNI Author Details".
  3. ^ a b Neuenschwander, Erwin. "Nägeli, Carl Wilhelm von". HLS-DHS-DSS.CH.
  4. ^ "VL People [per346]".
  5. ^ "Nägeli, Carl von – Deutsche Biographie".
  6. ^ W. T. Sedgwick and H. W. Tyler (1917). A short history of science. New York. p. 429.
  7. ^ Henry Harris. (1997). The Cells of the Body: A History of Somatic Cell Genetics. Cold Spring Harbor Laboratory, Plainview N.Y. p. 15. ISBN 978-0-87969-460-9
  8. ^ Texier, Catherine; Vidau, Cyril; Viguès, Bernard; El Alaoui, Hicham; Delbac, Frédéric (August 2010). "Microsporidia: a model for minimal parasite–host interactions". Current Opinion in Microbiology. 13 (4): 443–449. doi:10.1016/j.mib.2010.05.005. PMID 20542726.
  9. ^ Zuerich, ETH-Bibliothek. "Zeitschrift für wissenschaftliche Botanik (1844-1846)". E-Periodica (in German). Retrieved 27 March 2022.
  10. ^ Beiträge zur wissenschaftlichen Botanik. 4 Bände. Engelmann.
  11. ^ Naegeli, Carl Wilhelm von (7 August 1884). Mechanisch-physiologische Theorie der Abstammungslehre – via Max Planck Institute for the History of Science: Virtual Laboratory Library.
  12. ^ Kara Rogers. (2011). The Cell. Rosen Educational Services. pp. 136–137. ISBN 978-1-61530-314-4
  13. ^ Peter J. Bowler. (1989). Evolution: The History of an Idea. University of California Press. p. 248. ISBN 978-0-520-26128-0
  14. ^ International Plant Names Index.  Nägeli.


External links[edit]