Carnitine 3-dehydrogenase

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carnitine 3-dehydrogenase
EC no.
CAS no.9045-45-8
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a carnitine 3-dehydrogenase (EC is an enzyme that catalyzes the chemical reaction

carnitine + NAD+ 3-dehydrocarnitine + NADH + H+

Thus, the two substrates of this enzyme are carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is carnitine:NAD+ 3-oxidoreductase.


  • Aurich H, Kleber HP, Sorger H, Tauchert H (1968). "Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa" [Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]. Eur. J. Biochem. (in German). 6 (2): 196–201. doi:10.1111/j.1432-1033.1968.tb00437.x. PMID 4302217.
  • Schopp W, Sorger H, Kleber HP, Aurich H (1969). "Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa" [Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]. Eur. J. Biochem. (in German). 10 (1): 56–60. doi:10.1111/j.1432-1033.1969.tb00654.x. PMID 4310279.

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