Casein kinase 1, alpha 1

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CSNK1A1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CSNK1A1, CK1, CK1a, CKIa, HEL-S-77p, HLCDGP1, PRO2975, casein kinase 1 alpha 1
External IDs MGI: 1934950 HomoloGene: 111694 GeneCards: CSNK1A1
RNA expression pattern
PBB GE CSNK1A1 213086 s at fs.png

PBB GE CSNK1A1 206562 s at fs.png

PBB GE CSNK1A1 208865 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001025105
NM_001271741
NM_001271742
NM_001892

NM_146087

RefSeq (protein)

NP_001020276
NP_001258670
NP_001258671
NP_001883

NP_666199

Location (UCSC) Chr 5: 149.49 – 149.55 Mb Chr 18: 61.56 – 61.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene.[3]

Interactions[edit]

Casein kinase 1, alpha 1 has been shown to interact with Centaurin, alpha 1[4][5] and AXIN1.[6]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Tapia C, Featherstone T, Gómez C, Taillon-Miller P, Allende CC, Allende JE (Aug 1994). "Cloning and chromosomal localization of the gene coding for human protein kinase CK1". FEBS Letters. 349 (2): 307–12. doi:10.1016/0014-5793(94)00679-2. PMID 8050587. 
  4. ^ Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Letters. 517 (1-3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430. 
  5. ^ Dubois T, Kerai P, Zemlickova E, Howell S, Jackson TR, Venkateswarlu K, Cullen PJ, Theibert AB, Larose L, Roach PJ, Aitken A (Jun 2001). "Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins". The Journal of Biological Chemistry. 276 (22): 18757–64. doi:10.1074/jbc.M010005200. PMID 11278595. 
  6. ^ Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC (May 2002). "Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways". The Journal of Biological Chemistry. 277 (20): 17706–12. doi:10.1074/jbc.M111982200. PMID 11884395. 

Further reading[edit]

  • Veis A, Sfeir C, Wu CB (1998). "Phosphorylation of the proteins of the extracellular matrix of mineralized tissues by casein kinase-like activity". Critical Reviews in Oral Biology and Medicine. 8 (4): 360–79. doi:10.1177/10454411970080040101. PMID 9391750. 
  • Giaccia AJ, Kastan MB (Oct 1998). "The complexity of p53 modulation: emerging patterns from divergent signals". Genes & Development. 12 (19): 2973–83. doi:10.1101/gad.12.19.2973. PMID 9765199.