Caspase 5

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caspase 5, apoptosis-related cysteine peptidase
Symbol CASP5
Alt. symbols ICE(rel)III, ICH3
Entrez 838
HUGO 1506
OMIM 602665
RefSeq NM_004347
UniProt P51878
Other data
EC number
Locus Chr. 11 q22.2-q22.3

Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.[1]

See also[edit]


  1. ^ Martinon F, Tschopp J (2007). "Inflammatory caspases and inflammasomes: master switches of inflammation". Cell Death Differ. 14 (1): 10–22. doi:10.1038/sj.cdd.4402038. PMID 16977329. 

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: C14.008