Category talk:Genetic diseases and disorders

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WikiProject Genetics (Rated Category-class)
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Huntington's disease question[edit]

Congenital disorders -- http://en.wikipedia.org/wiki/Category:Congenital_disorders

Genetic_disorders -- http://en.wikipedia.org/wiki/Category:Genetic_disorders

The question to ponder is... Is Huntington's disease - http://en.wikipedia.org/wiki/Huntington%27s_disease genetic, congential or both? I'm sure it is genetic... yet think it is not considered congenital- 'cause onset isn't until late in life.

Interesting is that in the Huntingon's article they say 'inherited' --yet another synomym...? "Inherited diseases" could be a synomym for 'Genetic disorders' ...?

It would be good to have a discussion somewhere that sorts this out.

Double listing of congenital genetic disorders?[edit]

What is the WikiStyle on double listing of category listings? If a disease is indeed a congenital genetic disorder, ought it to be listed in both categories Category:Category:Genetic disorders AND Category:Congenital genetic disorders, OR ought it be listed only in the subcategory Category:Congenital genetic disorders? There is wide variation between articles in these two categories as to how this is handled (see the list in the article). Needs cleanup. N2e 02:45, 26 June 2006 (UTC)

Congenital genetic disorder category is a subcategory of Genetic disorders. So articles mustn't be listed in both of them. Yes, needs big cleanup. :( NCurse Nuvola apps edu science.png work 13:18, 7 August 2006 (UTC)
But, to be honest, Congenital genetic disorder should be merged into Genetic disorders. I understand that not all types of genetic disorders manifest early after birth (see Huntigton's disease), but the mutated gene or condition is inherited in both cases. NCurse Nuvola apps edu science.png work 13:21, 7 August 2006 (UTC)
There should really be one main category Genetic disorders. The small number of other genetic disorders that are not present at birth could be in a subcategory Acquired genetic disorders. --apers0n 17:38, 7 August 2006 (UTC)
I agree with Apers0n's suggestion re a small sub-category of GD for acquired GDs. And definitely concur that we do not need both GD and CGD categories. N2e 19:26, 7 August 2006 (UTC)
Then I ask a botowner to move all articles in CGD to GD. NCurse Nuvola apps edu science.png work 19:31, 7 August 2006 (UTC)

Done - Wikipedia:Bot_requests#Genetic_disorder_category... NCurse Nuvola apps edu science.png work 19:37, 7 August 2006 (UTC)

Moved. Ask me if you need anything else. alphaChimp laudare 04:28, 8 August 2006 (UTC)
Thanks! N2e 02:07, 15 August 2006 (UTC)

Acquired genetic disorder?!?[edit]

I have no idea what this new category means or why any of the diseases within are considered acquired. If it's a difference between a spontaneous germline mutation, that certainly is not acquired, as it is present since birth (see Smith-Magenis syndrome). If it's radiation or chemically induced mutation, then that again is not an acquired genetic disease. That's cancer or radiation sickness or whatever else you want to call it. As for Gulf War syndrome, I'm not going to wade into that hornet's nest but needless to say I don't believe that, if there is such thing as an acquired genetic disorder, these articles/categories belong in it! If you use the words acquired genetic disease to describe genetic mutation that occurs after birth, then the entirity of oncology, etc. would have to be there. In brief, I think that the category should be deleted unless further discussion can bring to light some aspect of medicine that my post-call state is overlooking. Sorry in advance if that's the case! InvictaHOG 15:35, 22 September 2006 (UTC)

You have a point, but in that case surely oncology should be a subcategory of Category:Genetic disorders anyway? --apers0n 07:48, 23 September 2006 (UTC)
There are several ways to approach the division of the genetic disorders category. One could go with "genetic diseases caused by mutation in a single gene" vs. "genetic diseases caused by mutations in multiple genes" and "polygenic genetic diseases." This would allow splits between, to give examples, 1) CF, 2)Omenn syndrome and 3) diabetes mellitus. However, it seems a rather cumbersome split. Alternatively, a mechanistic approach could be taken, with "deletions," "translocations," etc. but that complicates diseases which occur through multiple mechanisms. A division based on chromosomes such as "x-linked," "mitochondrial," "autosomal," and "epigenetic" might work, but there are syndromes which would fall in multiple categories still. Taking out obvious easy categories such as "DNA methylation" would not make much of a dent, but is simple to accomplish.
My best thought is that we not mess with the genetic disorders section too much. A different subcategory could be made for the "polygenic" diseases so that hypertension and diabetes can be separated out. A separate subcategory for "cancer genetics" is also appropriate, though the genetics for proliferative diseases which are not cancer will not fit there. Any way that I look at it, an acquired genetic disorder category does not make much sense - I still cannot think of a disease (other than benign and malignant cellular proliferations, aging, etc) which fits in the category. InvictaHOG 17:33, 23 September 2006 (UTC)
I have listed the category at CfD here --apers0n 05:14, 26 September 2006 (UTC)

Adding new disorder to list[edit]

Could someone add Fabry disease to this list? I've recently added a lot of info to the article for the condition, and would like it to be represented here, too!

Done. NCurse work 15:02, 8 October 2006 (UTC)


Adding another disorder to the list called idic15[edit]

Hi NCurse please add this syndrome to your list as well idic15 also called inverted duplication 15

I've added the [[Category:Genetic disorders]] to the article and started to clean it up. --apers0n 07:42, 14 October 2006 (UTC)

Thanks! for adding the category to the article. Will you also include the name of the disorder to the Genetci Disorders list? I can't see it in the alphabethical order. Thanks in Advance, Antal

I also changed the name of the page to Isodicentric 15 --apers0n 23:53, 14 October 2006 (UTC)
Thanks Apers0n! :) NCurse work 08:10, 15 October 2006 (UTC)

Not genetic[edit]

Since when is Gulf War Syndrome genetic, seriously, I saw it in the list, therefore I suggest removing it from the list. Series premiere (remake) (talk) 09:59, 21 July 2008 (UTC)