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Cayenne may refer to:
- Cayenne, the capital of French Guiana
- Cayenne pepper
- Cayenne (mascot)
- "Cayenne" (song), by the Beatles
- Porsche Cayenne, auto model
- Skywalk Cayenne, a German paraglider design
- Isle de Cayenne, island in French Guiana
| disambiguation page lists articles associated with the title Cayenne.
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