Cell Signaling Technology

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Cell Signaling Technology, Inc.
Privately held company
Industry Life Science, Manufacturing
Founded 1999
Founder Michael Comb
Headquarters Danvers, Massachusetts
Key people
Michael Comb, President and CEO
Roberto Polakiewicz, Chief Scientific Officer
Products Antibodies, ELISA Kits, ChIP Kits
Number of employees
300 — 350
Subsidiaries Cell Signaling Technology Japan, K.K.
Cell Signaling Technology (China) Limited
Cell Signaling Technology Europe, B.V.
Website www.cellsignal.com

Cell Signaling Technology, Inc. (CST) established in Beverly, Massachusetts in 1999, is a privately held company which produces antibodies and related reagents used to study cell signaling pathways. CST's current corporate headquarters are located in Danvers, Massachusetts.


Cell Signaling Technology, Inc. (CST) was founded in 1999 by scientists in the Cell Signaling group at New England Biolabs (NEB).[1]

Originally housed in the Cummings Center (Beverly, MA), CST moved to its current United States headquarters located at the former King’s Grant Inn (Danvers, MA) in late 2005.[1][2] Following extensive renovation,[3] the U.S. Green Building Council has certified the current headquarters as a LEED (Leadership in Energy and Environmental Design) certified facility in 2007.[4] In 2008 and 2009, CST expanded its overseas operations, establishing subsidiary offices in the People’s Republic of China, Japan, and the Netherlands.[5][6]

Cell Signaling Technology, Inc. (CST) was named as one of the “Top 100 Places to Work” in a 2009, 2010, 2011, 2012, 2013 survey published by the Boston Globe.[7]


CST maintains a curated, web-based bioinformatics resource known as PhosphoSitePlus, which details protein phosphorylation in human, mouse and rat. Curated information also includes other post-translational modifications, such as protein acetylation, methylation and ubiquitinylation. This freely accessible, on-line resource is funded in part through support from the NIH.[8][9]


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