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3D model (JSmol)
Molar mass 342.30 g·mol−1
Appearance white, hard powder
Odor odorless
Density 1.768 g/mL
Melting point 203.5 °C (398.3 °F; 476.6 K) (decomposes)
12 g/100mL
Solubility very slightly soluble in alcohol
insoluble in ether, chloroform
log P -5.03
Acidity (pKa) 12.39
Safety data sheet Sigma-Aldrich
NFPA 704
Flammability code 0: Will not burn. E.g., water Health code 1: Exposure would cause irritation but only minor residual injury. E.g., turpentine Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Cellobiose is a disaccharide with the formula [HOCH2CHO(CHOH)3]2O. Cellobiose, a reducing sugar, consists of two β-glucose molecules linked by a β(1→4) bond. It can be hydrolyzed to glucose enzymatically or with acid.[1] Cellobiose has eight free alcohol (OH) groups, one acetal linkage and one hemiacetal linkage, which give rise to strong inter- and intramolecular hydrogen bonds. It can be obtained by enzymatic or acidic hydrolysis of cellulose and cellulose rich materials such as cotton, jute, or paper.

Treatment of cellulose with acetic anhydride and sulfuric acid, gives cellobiose octoacetate, which is no longer a hydrogen bond donor (though it is still a hydrogen bond acceptor) and is soluble in nonpolar organic solvents.[2]


  1. ^ Cancerweb.ncl.ac.uk
  2. ^ Braun, G. (1943). "α-Cellobiose Octaacetate" (PDF). Organic Syntheses. Collected Volume 2: 124.  and Braun, G. (1937). "α-Cellobiose Octaacetate". Organic Syntheses. 17: 36. doi:10.15227/orgsyn.017.0036.