Cellobiose phosphorylase

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cellobiose phosphorylase
3s4a.jpg
Cellobiose phosphorylase dimer, Cellulomonas uda
Identifiers
EC number2.4.1.20
CAS number9030-20-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a cellobiose phosphorylase (EC 2.4.1.20) is an enzyme that catalyzes the chemical reaction

cellobiose + phosphate alpha-D-glucose 1-phosphate + D-glucose

Thus, the two substrates of this enzyme are cellobiose and phosphate, whereas its two products are alpha-D-glucose 1-phosphate and D-glucose.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is cellobiose:phosphate alpha-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Structural studies[edit]

As of late 2006, two structures have been solved for this class of enzymes, with PDB accession codes 2CQS and 2CQT.

References[edit]

  • Alexander JK (June 1968). "Purification and specificity of cellobiose phosphorylase from Clostridium thermocellum". The Journal of Biological Chemistry. 243 (11): 2899–904. PMID 5653182.
  • Ayers WA (November 1959). "Phosphorolysis and synthesis of cellobiose by cell extracts from Ruminococcus flavefaciens". The Journal of Biological Chemistry. 234: 2819–22. PMID 13795349.