Cells Alive System

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The Cells Alive System (CAS) is a line of commercial freezers manufactured by ABI Corporation, Ltd. of Chiba, Japan claimed to preserve food with greater freshness than ordinary freezing by using electromagnetic fields and mechanical vibrations to limit ice crystal formation that destroys food texture.[1][2][3] They also are claimed to increase tissue survival without having its water replaced by cryogenically compatible fluids; whether they have any effect is unclear.[4] The freezers have attracted attention among organ banking and transplantation surgeons,[5][6][7] as well as the food processing industry.[8]


  1. ^ Kelly, Tim (June 2, 2008). "Mr. Freeze—Norio Owada's freezing method can keep milk fresh for months. Livers, too". Forbes. Retrieved September 21, 2012.
  2. ^ Owada, N. (2009) "Quick Freezing Apparatus and Quick Freezing Method" US Patent Application
  3. ^ Owada, N. (2002) "Highly-efficient freezing apparatus and highly-efficient freezing method" US Patent 7,237,400
  4. ^ Wowk, B (Jun 2012). "Electric and magnetic fields in cryopreservation". Cryobiology. 64 (3): 301–3, author reply 304–5. doi:10.1016/j.cryobiol.2012.02.003. PMID 22330639.
  5. ^ Bruinsma, Bote G.; Uygun, Korkut (June 2017). "Subzero organ preservation: the dawn of a new ice age?". Current Opinion in Organ Transplantation. 22 (3): 281–286. doi:10.1097/MOT.0000000000000403. ISSN 1087-2418. PMC 5520671. PMID 28266941.
  6. ^ Uygun, Korkut; Yarmush, Martin L.; Toner, Mehmet; Izamis, Maria-Louisa; Uygun, Basak E.; Usta, O. Berk; Saeidi, Nima; Puts, Catheleyne F.; Bruinsma, Bote G.; Berendsen, Tim A. (July 2014). "Supercooling enables long-term transplantation survival following 4 days of liver preservation". Nature Medicine. 20 (7): 790–793. doi:10.1038/nm.3588. ISSN 1546-170X. PMC 4141719. PMID 24973919.
  7. ^ Szabó, Gábor (15 September 2012). "Hearts From the Deep Freezer? Novel Concept to Increase Safe Cardiac Preservation Times". Transplantation. 94 (5): 449. doi:10.1097/TP.0b013e3182637097. ISSN 0041-1337. PMID 22895610.
  8. ^ Cheng, Lina; Sun, Da-Wen; Zhu, Zhiwei; Zhang, Zi (2017). "Emerging techniques for assisting and accelerating food freezing processes: A review of recent research progresses". Critical Reviews in Food Science and Nutrition. 57 (4): 769–781. doi:10.1080/10408398.2015.1004569. PMID 26115177.

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