One Health Trust

From Wikipedia, the free encyclopedia
One Health Trust
Formation2009 (2009)
Headquarters5636 Connecticut Avenue NW,

PO Box 42735, Washington, D.C.

20015, U.S.A.
Location
Founder & President
Ramanan Laxminarayan
Websiteonehealthtrust.org

One Health Trust, formerly the Center for Disease Dynamics, Economics & Policy, is a public health research organization with offices in Washington, D.C., New Delhi, and Bangalore, India.[1]

Founded in 2010, the center announced its transition to becoming the One Health Trust in 2022[2] to expand the scope of the organization's research and work to include One Health Topics, such as animal health, planetary health, and climate change.[3]

Overview[edit]

The One Health Trust's team of economists, epidemiologists, social scientists, microbiologists, veterinarians, medical doctors, and disease modelers conduct research on antimicrobial resistance, zoonotic and vector borne diseases, environmental health, social determinants of health, vaccines and immunization, and other One Health topics.[4]

Primary activities[edit]

WHO Collaborating Center for Antimicrobial Resistance[edit]

The One Health Trust has been a World Health Organization Collaborating Center for antimicrobial resistance since 2020. The One Health Trust's researchers support the WHO in several activities to address the global health crisis of antimicrobial resistance.[5][6]

One Health Trust has published country-specific policy and information briefs reviewing progress in implementing national action plans on antimicrobial resistance as a World Health Organization Collaborating Center.[7]

Antimicrobial Resistance Research in Africa[edit]

As part of the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership consortium,[8] One Health Trust conducted data surveillance and analysis in Africa to determine the extent of antimicrobial resistance in the continent. The consortium included the African Society for Laboratory Medicine, Africa Centers for Disease Control and Prevention,[9] West African Health Organization, East Central & Southern Africa Health Community, IQVIA,[clarification needed] and Innovative Support to Emergencies, Diseases and Disasters.

The project was funded by the Fleming Fund[10] and involved data collection on antimicrobial resistance from public and private laboratories and pharmacies throughout Africa. The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership consortium reviewed 819,584 antimicrobial resistance records from 2016-2019 from 205 laboratories across the 14 African Union Member StatesBurkina Faso, Cameroon, Eswatini, Gabon, Ghana, Kenya, Malawi, Nigeria, Senegal, Sierra Leone, Tanzania, Uganda, Zambia, and Zimbabwe.[11]

The OxygenForIndia Initiative[edit]

The OxygenForIndia initiative was launched by One Health Trust and partnering institutions to address critical medical oxygen shortages in India.[12]

In April 2021, during a medical oxygen supply crisis,[13][14] OxygenForIndia deployed 20,000 reusable oxygen cylinders and 3,000 oxygen concentrators in 57 urban and rural centers across India. Currently, the One Health Trust team and partners are working to build a stable and reliable oxygen supply system[15] to avoid preventable deaths and improve pandemic preparedness. To achieve this objective, researchers are evaluating fiscal initiatives and building India's health system capacities.[16]

Global Antibiotic Resistance Partnership[edit]

The One Health Trust is a technical partner in the Global Antibiotic Resistance Partnership, which was initiated in 2008 to help low- and middle-income countries develop country-led strategies and policies to address antimicrobial resistance.[17][18][19][20]

Modeling Infectious Diseases in Healthcare Network (MInD – Healthcare)[edit]

One Health Trust is a member of the U.S. Centers for Disease Control and Prevention's MInD – Healthcare Network, which supports transmission modeling research to get insights on the drivers of healthcare-associated infections and antibiotic-resistant infections and estimate the benefits of preventive measures.[21]

Affordable Medicines Facility - Malaria[edit]

The Affordable Medicines Facility — Malaria grew from a 2004 Institute of Medicines (IOM) report co-authored by One Health Trust's Dr. Ramanan Laxminarayan.[22][23] The project addressed the issue of rising antimalarial drug resistance against the most commonly used malaria treatment at the time, chloroquine, by finding ways to get artemisinin-based combination therapies — the most effective malaria treatments known — into private pharmacies and village shops.[24][25]

Through negotiating bulk orders and subsidies, the Affordable Medicines Facility - Malaria team worked to leverage the extensive existing private-sector infrastructure in Africa to get good medicines where there were none before, lowering prices of effective antimalarials in rural Africa.[26] The scheme, which ran from 2010 through 2012, was tested in seven African countries and was found successful in increasing the number of outlets stocking artemisinin-based combination therapies and lowering prices.[27]

PhD program in Data Sciences for Global Health in partnership with Birla Institute of Technology & Science, Pilani[edit]

The One Health Trust, in partnership with Birla Institute of Technology & Science (BITS) in Pilani, India, has a PhD program in Data Sciences for Global Health to provide training in global health issues and research methodology with fieldwork and data analysis.[28] This program is full-time.[29]

ResistanceMap[edit]

The One Health Trust's ResistanceMap is a collection of tools summarizing national and subnational data on antimicrobial use and resistance globally.[30] Since its launch in 2010, ResistanceMap has been used to inform researchers, policy makers, and the public of important trends in drug resistance and antibiotic use.[31] [32]  

In 2015, ResistanceMap was updated with a new design interface, expanded tools, and the addition of antibiotic use and resistance data from several low- and middle-income countries in Africa, Asia and South America.[33]

One World, One Health Podcast[edit]

The One World, One Health podcast[34] by the One Health Trust was launched in 2022. The podcast is interview-style and the host, Maggie Fox, talks to scientific researchers about topics including pandemics, antimicrobial resistance, the impact of deforestation on human health, among other related issues.

References[edit]

  1. ^ "About Us". One Health Trust. Retrieved 19 June 2023.
  2. ^ "CDDEP is becoming the One Health Trust". Retrieved May 24, 2022.
  3. ^ "One Health". www.who.int. Retrieved 2023-11-28.
  4. ^ "Research Areas". One Health Trust.
  5. ^ "World Health Organization GLASS WHO AMR CC Network". World Health Organization.
  6. ^ "WHO Collaborating Centres". World Health Organization.
  7. ^ "WHO- Mali National Action Plan on AMR". World Health Organization. Retrieved 17 February 2023.
  8. ^ "MAAP-African Society for Laboratory Medicine". African Society for Laboratory Medicine.
  9. ^ "Africa Centres for Disease Control and Prevention". Wikipedia- Africa Centres for Disease Control and Prevention.
  10. ^ "Announcing the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project". Fleming Fund. Retrieved 4 April 2019.
  11. ^ "Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) Country Reports". Africa CDC. Retrieved 20 July 2023.
  12. ^ "India's Crisis Marks a New Phase in the Pandemic". The New Yorker. Retrieved 13 May 2021.
  13. ^ "Critical oxygen shortage underlines severity of India's Covid crisis". Financial Times.
  14. ^ "Explained: Why India is facing oxygen shortage during 2nd Covid wave". India Today. Retrieved 22 April 2021.
  15. ^ "Healthcube enabling distribution of medical oxygen across India through OxygenForIndia initiative by CDDEP". The Economic Times. Retrieved 6 May 2021.
  16. ^ "No shortage in future: India unveils blueprint for a national medical oxygen grid". South First. Retrieved 19 October 2022.
  17. ^ "The Global Antibiotic Resistance Partnership (GARP)". Ducit Blue Solutions.
  18. ^ "The Evolution of the Global Antibiotic Resistance Partnership". AMR Control- Overcoming Global Antimicrobial Resistance. Retrieved 12 September 2016.
  19. ^ "Antibiotic resistance: AMR a health threat in Uganda". DownToEarth. Retrieved 23 January 2020.
  20. ^ "Could vaccines save us from antimicrobial resistance?". Gavi- The Vaccine Alliance. Retrieved 26 July 2022.
  21. ^ "Modeling Infectious Diseases in Healthcare Network (MInD – Healthcare)". Centers for Disease Control and Prevention.
  22. ^ "Affordable Medicines Facility-malaria". Wikipedia- Affordable Medicines Facility-malaria.
  23. ^ "A Global Subsidy: Key to Affordable Drugs for Malaria?". HealthAffairs. Retrieved November 27, 2009.
  24. ^ "Affordable Medicines Facility-Malaria (AMFm) - CDDEP". Resources. Retrieved 20 July 2015.
  25. ^ "For malaria, we just can't afford to use cheap drugs". Financial Times.
  26. ^ "Subsidies Help Get Modern Malaria Drugs To Millions In Africa". npr. Retrieved 19 September 2012.
  27. ^ "Effect of the Affordable Medicines Facility—malaria (AMFm) on the availability, price, and market share of quality-assured artemisinin-based combination therapies in seven countries: a before-and-after analysis of outlet survey data". The Lancet. Retrieved 1 December 2012.
  28. ^ "BITS Pilani collaborates with Washington based One Health Trust to offer PhD in Data Sciences". Financial Express. Retrieved 20 December 2022.
  29. ^ "BITS Pilani, One Health Trust invite applications for PhD in Data Science for Global Health; check eligibility, how to apply". The Indian Express. Retrieved 20 December 2022.
  30. ^ "CDDEP Maps Dangerous Trends in Antibiotic Resistance on a Global Scale". jpiamr. Retrieved 17 September 2015.
  31. ^ "Tracking global trends in the effectiveness of antibiotic therapy using the Drug Resistance Index". EurekAlert. Retrieved 17 April 2019.
  32. ^ "Antibiotic Resistance Getting Worse Globally, But Fixes Could Be Simple". National Geographic. Retrieved 17 September 2015.
  33. ^ "CDDEP releases "The State of the World's Antibiotics, 2015" Report". SIDP- Society of Infectious Diseases Pharmacists. Retrieved 21 September 2015.
  34. ^ "One World, One Health Podcast".

External links[edit]