Cerebral hyperperfusion syndrome
Cerebral hyperperfusion syndrome, also known as reperfusion syndrome, is a dysregulated state of cerebral blood flow following the restoration of arterial blood flow to the brain, usually following treatment of carotid artery stenosis.[1] Risk factors include hypertension, particularly high blood pressures in the first few days following revascularization and bilateral stenosis.
Symptoms[edit]
The first symptom is usually severe headache, and a headache in the setting of recent carotid endarterectomy or carotid stenting should prompt a return to the hospital and close attention by clinicians. Symptoms may progress to seizures and coma in severe cases.
Treatment[edit]
Treatment is control of the blood pressure, often with continuous intravenous antihypertensives medicines in the intensive care setting.[2] Seizures may require treatment with anti-seizure medication.
References[edit]
- ^ Farooq, MU; Goshgarian, C; Min, J; Gorelick, PB (2016). "Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting". Experimental & Translational Stroke Medicine. 8 (1): 7. doi:10.1186/s13231-016-0021-2. PMC 5012059. PMID 27602202.
- ^ Kirchoff-Torres, KF; Bakradze, E (19 March 2018). "Cerebral Hyperperfusion Syndrome After Carotid Revascularization and Acute Ischemic Stroke". Current Pain and Headache Reports. 22 (4): 24. doi:10.1007/s11916-018-0678-4. PMID 29556806.