Pascarella was born in Rome and initially was a painter. His literary activity began in 1881 with the publication of sonnets in Romanesco dialect. In the same period he made friends with Gabriele D'Annunzio. He made a series of journeys through Africa, India and the Americas in 1882–1885. On his return to Rome he published the collection Villa Glori, who was hailed as a masterwork by Giosuè Carducci. Also well received was the imaginative La scoperta dell'America (1893).
In 1905 Pascarella began Storia nostra, a history of Rome which was planned as a sequence of 350 sonnets, but was left unfinished after 270 had been written.
He founded in 1904 with other artists, among which Giuseppe Ferrari, the group "XXV della campagna romana".
^M. C. Cola, Giuseppe Ferrari, in Dizionario biografico degli italiani Treccani, volume 46, 1996.
^D. Armocida, Il Fondo di Cesare Pascarella: storia e documenti, Roma, Scienze e lettere editore, 2011, pp. 323-348 (from: «Atti della Accademia Nazionale dei Lincei. Classe di Scienze Morali, Storiche e Filologiche. Rendiconti», Serie IX, Vol. XXI, Fasc. 1-2, 2010).
Rendina, Claudio (2000). Enciclopedia di roma. Rome: Newton & Compton.