ChGn

From Wikipedia, the free encyclopedia
Jump to: navigation, search
CSGALNACT1
Identifiers
Aliases CSGALNACT1, CSGalNAcT-1, ChGn, beta4GalNAcT, chondroitin sulfate N-acetylgalactosaminyltransferase 1
External IDs MGI: 2442354 HomoloGene: 23099 GeneCards: CSGALNACT1
RNA expression pattern
PBB GE ChGn 219049 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001130518
NM_018371

NM_001252623
NM_172753

RefSeq (protein)

NP_001123990
NP_060841

NP_001239552.1
NP_766341.4
NP_001239552
NP_766341

Location (UCSC) Chr 8: 19.4 – 19.76 Mb Chr 8: 68.36 – 68.74 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is an enzyme that in humans is encoded by the CSGALNACT1 gene.[3][4][5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H (Feb 2007). "Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage". The Journal of Biological Chemistry. 282 (6): 4152–61. doi:10.1074/jbc.M606870200. PMID 17145758. 
  4. ^ Sato T, Gotoh M, Kiyohara K, Akashima T, Iwasaki H, Kameyama A, Mochizuki H, Yada T, Inaba N, Togayachi A, Kudo T, Asada M, Watanabe H, Imamura T, Kimata K, Narimatsu H (Jan 2003). "Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate". The Journal of Biological Chemistry. 278 (5): 3063–71. doi:10.1074/jbc.M208886200. PMID 12446672. 
  5. ^ "Entrez Gene: ChGn chondroitin beta1,4 N-acetylgalactosaminyltransferase". 

Further reading[edit]

  • Gotoh M, Sato T, Akashima T, Iwasaki H, Kameyama A, Mochizuki H, Yada T, Inaba N, Zhang Y, Kikuchi N, Kwon YD, Togayachi A, Kudo T, Nishihara S, Watanabe H, Kimata K, Narimatsu H (Oct 2002). "Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis". The Journal of Biological Chemistry. 277 (41): 38189–96. doi:10.1074/jbc.M203619200. PMID 12163485. 
  • Uyama T, Kitagawa H, Tamura Ji J, Sugahara K (Mar 2002). "Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate". The Journal of Biological Chemistry. 277 (11): 8841–6. doi:10.1074/jbc.M111434200. PMID 11788602. 
  • Kitagawa H, Uyama T, Sugahara K (Oct 2001). "Molecular cloning and expression of a human chondroitin synthase". The Journal of Biological Chemistry. 276 (42): 38721–6. doi:10.1074/jbc.M106871200. PMID 11514575.