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A chagoma is an inflammatory nodule at the bite site of the reduviid bug which transmits Chagas disease,[1] not to be confused with Romana's sign which is periorbital soft tissue and lymphoid swelling which occurs when the T. cruzi protozoan that causes Chagas disease enters through the conjunctiva.[2]


  1. ^ Schmutzhard, Erich; Helbok, Raimund (2014). "Rickettsiae, protozoa, and opisthokonta/metazoa". Neurologic Aspects of Systemic Disease Part III. Handbook of Clinical Neurology. 121. pp. 1403–43. doi:10.1016/B978-0-7020-4088-7.00096-1. ISBN 978-0-7020-4088-7. PMID 24365428.
  2. ^ Kirchhoff, Louis V. (2011). "American Trypanosomiasis (Chagas Disease) * *All the material in this chapter is in the public domain, with the exception of the borrowed figures". American Trypanosomiasis (Chagas Disease). pp. 689–95. doi:10.1016/B978-0-7020-3935-5.00099-9. ISBN 978-0-7020-3935-5.