Charles A. Dinarello

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Charles A. Dinarello
Charles Dinarello, 2010
Born (1943-04-22) April 22, 1943 (age 81)
Alma materYale University
Known forResearch on inflammatory cytokines
AwardsErnst Jung Prize (1993)
Crafoord Prize (2009)
Albany Medical Center Prize (2009)
Paul Ehrlich and Ludwig Darmstaedter Prize (2010)
Tang Prize (2020)
Scientific career
InstitutionsUniversity of Colorado Denver

Charles A. Dinarello (born April 22, 1943) is a professor of medicine at the University of Colorado at Denver. He is an expert on inflammatory cytokines, specifically Interleukin 1.

Education and career[edit]

Dinarello received his Doctor of Medicine in 1969 at Yale University and since 1996, he is Professor of Medicine at University of Colorado School of Medicine. He is also Professor of Experimental Medicine at the Radboud University Medical Center in Nijmegen, The Netherlands. Dinarello is considered one of the founding fathers of cytokines having purified and cloned interleukin-1.[1] This important step established the validation of cytokines as mediators of disease, particularly of inflammation. Current studies blocking IL-1 in humans supports Dinarello's and his co-workers pivotal contributions to cytokine biology and the pathogenesis of inflammatory diseases.[2]

He is fluent in English, Italian and German.[citation needed]



  1. ^ Dinarello, Charles A (2015-03-31). "The history of fever, leukocytic pyrogen and interleukin-1". Temperature. 2 (1): 8–16. doi:10.1080/23328940.2015.1017086. ISSN 2332-8940. PMC 4843879. PMID 27226996.
  2. ^ Garlanda, Cecilia; Dinarello, Charles A.; Mantovani, Alberto (2013). "The Interleukin-1 Family: Back to the Future". Immunity. 39 (6). Elsevier BV: 1003–1018. doi:10.1016/j.immuni.2013.11.010. ISSN 1074-7613. PMC 3933951.
  3. ^ Press Release of the Royal Swedish Academy of Sciences Archived July 8, 2011, at the Wayback Machine
  4. ^ Immune system researchers win $500K medical prize
  5. ^ "Charles Dinarello". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 29 January 2016. Retrieved 29 January 2016.
  6. ^ Tang Prize 2020

External links[edit]